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过程工程学报 2012
Salting-out Extraction of Lactic Acid from Fermentation Broth
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Abstract:
Salting-out extraction was used for recovery of lactic acid from fermentation broth.The different hydrophilic organic solvents-inorganic salts systems were investigated for their extraction ability.The results showed that the K2HPO4-methanol and K2HPO4-ethanol systems appeared to be favorable.The partition coefficient and recovery rate of lactic acid reached up to 4.01 and 86.0% for the system of 25%(ω) K2HPO4-26%(ω) methanol,when the concentration of lactic acid was 167 g/L in the broth.For the system of 14%(ω) K2HPO4-30%(ω) ethanol,the partition coefficient and recovery rate of lactic acid reached up to 3.23 and 90.6%.The removal rate of glucose,cells and proteins reached 67.3%,100% and 85.9%,respectively.