SYNTHESIS OF HYDROGEN-BONDING POLYMERIC ADSORBENTS AND PREPARATION OF HIGHLY PURIFIED FLAVONOIDES EXTRACTS FROM SEA BUCKTHORN LEAVES
氢键吸附树脂的合成及高纯度沙棘叶黄酮的制备

Based on results of adsorption property of four selected commercial adsorbents,a series of high selectivity polymeric adsorbents were synthesized based on the copolymerization of methyl acrylate (MMA) and divinylbenzene (DVB).The amino functional group was introduced into the adsorbent matrix to produce the hydrogen-bonding interaction with the flavonoides,which has the typical phenolic hydroxyl structure.The influences of the hydrophobic intensity of the adsorbent and the spacer arm length of the functional group on the adsorption property were investigated.When the adsorption was carried out in the aqueous environment reasonable hydrophobic affinity is necessary to assist the hydrogen bonding.In addition,the length of the spacer arm of the functional group affected the adsorption ability owing to the large size of flavonoides molecule.The adsorbent XM20.2 showed the optimal adsorption capacity and selectivity to the flavonoides.Experimental parameters for adsorption and elution were optimized.After purification of the crude extract of sea buckthorn leaves,the content of flavonoides increased from 10.4% to above 50%.The adsorbent showed good reproducibility.