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EPMA Journal  2012 

Predictive and preventive strategies to advance the treatments of cardiovascular and cerebrovascular diseases: the Ukrainian context

DOI: 10.1186/1878-5085-3-12

Keywords: Cardiovascular diseases, Hemodynamics, Capillaroscopy, Predictive diagnostics, Preventive strategies, Personalized medicine

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Abstract:

The background level of functioning of nearly all organs and systems is important for providing blood pressure in the cardiovascular system. Today, nobody can deny the fact that any organ dysfunction can be caused by decrease or sudden stop of the blood supply. A theory, which exists in medicine years long, stating that any metabolic disturbance is the primary pathogenetic factor of cardiovascular diseases (CVDs) and disorders in blood supply level is the secondary one is losing its significance now [1-13].CVDs are an actual problem nowadays because of high rates of morbidity, mortality, and disability, indicating the low efficiency of applied methods for vascular diagnosis and treatment [7,10,11,14-17]. Today, occupying first place by spreading cardiovascular diseases cause more than half of all deaths and one-third of disability, mainly due to uncompensated cardiovascular conditions—heart attacks and strokes (according to statistics from WHO and Ministry of Health of Ukraine).Three-fourths of the population is suffering from cardiovascular pathologies in Ukraine alone, and it causes death in 62.5% of cases; that is much higher than in developed countries. Recently the spreading of ischemic heart disease has increased in Ukraine from 10 thousands to more than 20 thousands per 100 thousands of the population, and more than 5 million patients with hypertonic disease are registered in Ukraine [10,11].When we analyzed the statistics in Ukraine, Europe, and the world [8,17], we observed the following tendency: 20 years ago, people older than 40–50 years had CVDs, while today the age of such patients is older than 30 years. Lately, there is a negative tendency in Ukraine: strokes began to be more frequently observed in teenagers and children of preschool and junior school age [6,10].To the greatest regret, today's statistics of Ukraine and other countries of the world represent mainly negative tendencies except for positive Japanese experience [8,16], namely cardiovascul

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