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One-pot tandem cyclization of enantiopure asymmetric cis-2,5-disubstituted pyrrolidines: Facile access to chiral 10-heteroazatriquinanesDOI: 10.3762/bjoc.9.32 Keywords: cis-2 , 5-disubstituted pyrrolidine , 10-heteroazatriquinane , tandem cyclization , X-ray single-crystal diffraction analysis Abstract: A series of chiral 10-heteroazatriquinanes were synthesized from enantiopure asymmetric cis-2,5-disubstituted pyrrolidines through a one-pot tandem cyclization procedure. The structures and configurations of these new chiral 10-heteroazatriquinanes are confirmed by X-ray single-crystal diffraction analysis.
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