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OALib Journal期刊
ISSN: 2333-9721
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p -Dimethylaminopyridine (DMAP): A highly efficient catalyst for one pot, solvent free synthesis of substituted 2-amino-2-chromenes under microwave irradiation

Keywords: 2-amino-2-chromenes , multicomponent , p-dimethylaminopyridine , microwave irradiation.

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Abstract:

A highly efficient, green and expeditious method is described for the synthesis of substituted 2-amino-2-chromenes employing one pot three component condensation of aromatic aldehydes, malononitrile and activated phenol in presence of p-dimethylaminopyridine (10 mol %) as a catalyst under microwave irradiation. The present method is operationally simple and offers many advantages such as high yield, short reaction time and simple workup.

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