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Pegylated Interferon and Ribavirin Treatment of Chronic Hepatitis C Coinfection in a Patient with Human Immunodeficiency Virus Infection

Keywords: HIV , HCV antibodies , coinfection , pegylated interferon alpha 2a , ribavirin.

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Abstract:

Human immunodeficiency virus (HIV) and hepatitis C virus (HCV) coinfection is seen frequently due to similar routes of transmission. In coinfected patients, progression of chronic hepatitis C (CHC) infection is accelerated. In this study, a 44-year old male patient with HIV/HCV (genotype 1b) coinfection is evaluated. For the treatment of CHC, pegylated interferon alpha 2a 180 mg per week and ribavirin 1000 mg/day were used for 48 weeks and sustained virologic response was achieved. During the course of CHC treatment no adverse effect was seen.

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