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Bioautomation 2009
Quasi-Stationary Approximation of a Dynamical Model of MicroRNA Target Regulation. Part II. Application of the QSSA TheoremKeywords: QSSA theorem , MicroRNA target regulation , Proteins , Post-initial state Abstract: The QSSA theorem is applied to the dynamical model of microRNA target regulation after special selection of model variables, presented in Part I of this article. On the basis of this theorem the complete model, represented as a system of seven nonlinear ordinary differential equations, is reduced to a degenerate one, comprising only two ordinary differential equations. As a result it is proved that the proteins, produced by miRNAs are identified to play a driving role of the dynamical behaviour of the genetic process investigated, but in post-initial (or quasi-stationary) stage.
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