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Koomesh  2012 

The relationship between coronary risk factors and coronary artery involvement based on angiogrpahy findings

Keywords: Coronary artery disease , Risk factors , Angiography , Coronary angiography , Coronary stenosis

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Abstract:

Introduction: Obstructive coronary diseases have been found to be the most important for theassessment of cardiovascular diseases. This survey was designed to determine the relationship betweenischemic risk factors and tract disease coronary artery.Materials and Methods: This cross-sectional study was conducted on 5442 patients who referred toGolestan’s Kosar center for angiography in the years 2008 to 2009. The outcome variable was the resultsof angiography, positive or negative. Risk factors including age, gender, body mass index (BMI), waistcircumference (WC), waist to hip ratio (WHR), blood pressure, diabetes mellitus, smoking and drugaddiction in the samples were evaluated and recorded for all patients. Multivariate analysis was performedby logistic regression.Results: We found significant differences between age, diabetic mellitus and hypertension status inpatients with positive coronary angiogram versus patient with negative coronary angiogram in both sexes.Also, regression analysis showed hypertension (OR=1.8), abnormal fasting blood sugar (OR=1.2), malegender (OR=2.2), WHR (OR=1.4) and opiates addiction (OR=1.3) increased significantly the probability ofcoronary arteries involvement.Conclusion: In patients with positive coronary angiogram, fasting blood sugar, hypertension and age inboth sexes, and WHR and opium addiction in females may be stronger predictors of extent of CAD.Prevention of these risk factors may be effective in controlling the progress of CAD.

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