Synthesis of β-Amino Carbonyl Compounds via Mannich reaction using sulfated MCM-41

One-pot three-component reaction of anilines with ketone and aldehyde leads to the formation of β-amino carbonyl compounds in the presence of sulfated MCM-41 as a recyclable solid acid catalyst. This method has several advantages like simple and easy work-up procedures with shorter reaction time and high yields of Mannich products.