Nitric Oxide In Health And Diseases

Nitric Oxide (NO) is color less, readily diffusible, highly reactive lipophilic and chemically unstable Free radical gas. NO is formed form arginine by enzyme nitric Oxide synthase. No acts in a paracrine or even autocrine manner. It causes asodilatation, act as neurotransmitter, Prevent Platelet aggregation and also play important role in macrophase function. Deficiency leads to, increase vascular tone, reduced thrombolitic activity. Use of NO in pediatric pulmonary hypertension and in sexual dysfunction is increases day by day. The discovery of NO as an essential effectors of many Biological