The Effect of Epinephrine On The Development of oogenesis Of Mice (Mus Musculus) Strain of Japanese

When stress persists continuously and repeatedly, it will automatically increase the epinephrine in the body in which excessive consequently can provide interference on various body systems. In the event of physical stressors can affect the frequency and amplitude of pulsatile gonadotropin-releasing hormone (GnRH). It is important for the secretion of follicle-stimulating hormone (FSH) and luteinizing hormone (LH). Additionally stressors can also activate the sympathetic nervous system. If the increase is excessive pulsation can reduce and stop the secretion of follicle-stimulating hormone (FSH) and luteinizing hormone (LH). Decrease in Follicle-stimulating hormone (FSH) and luteinizing hormone (LH) will inhibit the growth of ovarian follicles and decrease the synthesis of estrogen and progesterone in the ovaries. Decreased synthesis of estrogen and progesterone can cause a decrease in the number of ovarian follicles (Speroff, 1994).The study population was female mice derived from laboratory Biomedic Andalas University in Padang. Mice used were 2-3 months old, weighing an average of 25-35 grams. The Effect of Epinephrine on the Development of Oogenesis of Mice (mus musculus) Strain of Japanese, is the growth of primary follicles in which a decline in the number of primary follicles ranging from provision of 0.002 mg / ml, epinephrine administration lowered formation of secondary follicles at a concentration of 0.004 mg / ml and above but no decrease in concentration of 0.002 mg / ml, epinephrine administration lowered formation of tertiary follicles at a concentration of 0.004 mg / ml, 0.006 mg / ml, 0.008 mg / ml and 0.01 mg / ml and no decrease in concentration of 0.002 mg / ml, epinephrine administration did not reduce the formation of follicle de Graaf and administration of epinephrine significantly reduce the formation of the corpus luteum at a concentration of 0.004 mg / ml, 0.006 mg / ml, 0.008 mg / ml and 0.01 mg / ml and no decrease in concentration of 0.002 mg / ml.