Combination of pregabalin and palmitoylethanolamide (PEA) for neuropathic pain treatment

30 patients ranging between 32 to 78 years, suffering from neuropathic pain, were treated with pregabalin and palmitoylethanolamide for 45 days. All patients have completed the study and no side effect was reported; in all patients it has been observed a significant reduction of pain intensity that was associated to a better quality of the sleep. The improvement of the clinical symptomatology was associated to a recovery of quality of sleep and to a good subjective evaluation of the effectiveness of the therapy. In conclusion, the efficacy of a new multitherapeutic approach for neuropathic pain, based on pregabalin + palmitoylethanolamide has been proved; the therapy showed to be safe and allows patients to have a better quality of life.