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Factors associated with dyslipidemia in seropositive patients for human immunodeficiency virus. Fadevic study.

Keywords: Dyslipidemias , HIV Infections , Anti-Retroviral Agents , Risk factors.

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Abstract:

Introduction: with the argument of life expectancy of the people affected by HIV/AIDS, new challenges of health emerged. The dyslipidemias, in special, are presentedas a complication of the infection by the virus and the antiretroviral treatment(ARV). In Cartagena, Colombia the prevalence of dyslipidemia in HIV positive, thesociodemographic and clinical characteristics, and its associated factors are unknown.Objective: to determine the prevalence and classification of dyslipidemias in HIV (+)patients and to know what factors are associated with the lipid alteration.Methods: It was carried out an observational and cross sectional study. Data wasobtained from the interviews to the patients, the health staff that is responsible of theircare and from the review of clinical histories. The prevalence of dyslipidemia in thestudied individuals was estimated and the possible factors associated with alteration ofthe lipid profile were analyzed.Results: there was analyzed the data from 221 patients. The prevalence of dyslipidemiawas 80.0%, being the isolated hypertriglyceridemia the most frequent type. With morefrequency, the patients with dyslipidemia were men and they had higher admissionsand higher weight. There were found positive correlations between the values of lipidand age, hemoglobin and CD4 and CD8 counts. Also, total cholesterol, LDH and HDLpresented a negative correlation with the viral charge. People without ARV treatmenthad total cholesterol, LDL and HDL levels significantly lower than people in treatment.Conclusions: dyslipidemia is a very frequent complication in patients with HIV/AIDSfrom Cartagena. It is a priority to design contextualized guidelines of management andefficient interventions. Rev.cienc.biomed. 2012; 3(2): 267-274RESUMEN:Introducción: con el aumento de la expectativa de vida de las personas afectadasde VIH/SIDA, emergieron nuevos retos de salud. Las dislipidemias, en especial, sepresentan como una complicación tanto de la infección por el virus como del tratamientoantirretroviral (ARV). En Cartagena, Colombia, se desconoce la prevalencia dedislipidemia en personas seropositivas, las características sociodemográficas, clínicasy factores asociados.Objetivo: determinar la prevalencia y clasificación de las dislipidemias en pacientesVIH (+) y conocer qué factores se asocian a la alteración lipídica.Materiales y métodos: se realizó estudio observacional, de corte transversal. Losdatos se obtuvieron a partir de entrevistas a los pacientes, el personal de saludresponsable de su cuidado y la revisión de las historias clínicas. Se calculó l

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