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The Evaluation of Cord Blood Magnesium Level in Neonates of Magnesium

Keywords: Pre-eclampsia , Eclampsia , Magnesium sulphate.

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Abstract:

This case control study was carried out on 35 neonates born to pre-eclamptic/eclamptic mothers treated withmagnesium sulphate and 35 neonates born to normal healthy mothers. Cases and controls were selected by inclusion-exclusion criteria irrespective of body weight and maturity of the babies. Magnesium sulphate administered to mother instudy group was according to Pritchard’s intramuscular regime (1984).The cord blood samples were collected just after birth in both study and control group and magnesium level wasestimated by calorimetric method. Magnesium level was found to be significantly higher in study group (6.0305±0.08047)than controls (1.916± 0.300; p = 0.0001). There was a significant difference in Apgar scores of study and control group. Anegative weak linear correlation was found between cord blood magnesium level and different neonatal parameter likeapgar score, birth weight and gestestional age. A weak positive linear correlation was found between magnesium level andneonatal mortality which was also not significant.

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