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OALib Journal期刊
ISSN: 2333-9721
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SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL EVALUATION OF PYRIDINE BASED THIAZOLIDINONES Synthese, Charakterisierung und antimikrobiellen BEWERTUNG DER Pyridinbasis Thiazolidinone

Keywords: Thiazolidinone, Antimicrobial, Schiff base, Pyridine

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Abstract:

The amino pyridine which has been used as a key material for the present synthesis. Schiff bases participating active role for the formation of thiazolidinones derivatives. For the preparation of these Schiff bases here we have used amino pyridine and different type of aromatic aldehydes. The successfully formed Schiff bases are further reacted with thioglycolic acid in the presence of zinc chloride the title compound was obtained. In addition these resultants were screened for their antimicrobial activity against different bacterial and fungal strains. The synthesized thiazolidinone derivatives were characterized by IR, 1H NMR, 13C NMR and elemental analyses studies

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