Effect of Diet Contains Sesame Seed on Adult Wistar Rat Testis Efecto de la Dieta con Semillas de Sésamo sobre el Testículo de la Rata Wistar Adulta

Studies show that some antioxidants are effective in improving male infertility. According to several antioxidant compounds that exist in sesame seed, this study was designed and carried out to the effects of sesame seed diet consumption on adult male rats testis structure and sex hormones. This experimental study was carried out on 30 adults Wistar rat, 200 g that obtained from laboratory animal center at Kashan University of Medical Sciences. Rats were divided into experimental and control groups randomly. The control group received standard diet and experimental group received diet containing 70% standard diet and 30% sesame seed after weaning for 12 weeks. At the end of the study, testis weight and volume were measured and seminiferous tubules; lumen epithelium diameter, LH, FSH and testosterone concentrations were evaluated. Data was analyzed by SPSS software and t-test. P< 0.05 was considered to significant level. Bodyweight rats, weight and volume testis and percentage volume seminiferous tubules vessels in two groups were not significant. The mean cells number and motility of sperm in left epididym, number of cells epithelium and percentage volume of epithelial, lumen and interstitial of this tubules were extremely significant (P<0.0001) in the experimental group compared to control. LH concentration increased significantly in the experimental group compared to control (P<0.03). Sesame seed intake improved testicular parameters, fertility and sperm production in males. Estudios demuestran que algunos antioxidantes son eficaces en la mejora de la infertilidad masculina. Debido a la presencia de varios compuestos antioxidantes que existen en la semilla de sésamo, este estudio fue dise ado y realizado para evaluar los efectos de su consumo sobre la estructura testicular y las hormonas sexuales de ratas macho adultas. Se utilizaron 30 ratas Wistar adultas de 200 g obtenidas desde el centro laboratorio animal de Kashan University of Medical Sciences. Las ratas se dividieron en grupos experimental y de control. El grupo control recibió una dieta estándar y el grupo experimental una dieta que contenía 70% de dieta estándar y 30% de semillas de sésamo, después del destete durante 12 semanas. Al final del estudio, se midieron el peso y volumen de los testículos y túbulos seminíferos, diámetro luminal epitelial, y las concentraciones de LH, FSH y testosterona. Los datos fueron analizados mediante t-test con el programa SPSS. Fue considerado significativo un valor P<0,05. El peso corporal de las ratas, peso y volumen testicular, y el porcentaje volumétrico