Pace and sotalol – three case reports of the benefits and potential hazards associated with sotalol administration in sinus node dysfunction

The sinus node dysfunction is associated with conduction system disease and supraventriculartachyarrhythmias (atrial fibrillation and atrial flutter). The only effective treatment for patients withchronic symptomatic sinus node dysfunction is pacemaker therapy. In tachy-brady syndrome patients, inaddition to pacemaker therapy, the pharmacological treatment is necessary to avoid tachycardiaepisodes. Because of the frequent paroxysmal atrial fibrillation episodes a good choice to maintain thesinus rhythm is represented by sotalol. This article will present three patients that provide examples ofbeneficial effects of sotalol and also on the risk of severe adverse events in some cases.