Image analysis of the normal human retinal vasculature using fractal geometry

The main objective of this study is to determine a global index of the geometric complexity of the human retinal vascular networkusing the fractal geometry. Material and Methods: The fractal analysis of digital retinal images was performed with the Image J fractal analysissoftware and the fractal dimensions were calculated using the standard box-counting method. Results: The mean fractal dimension of normalretinal vascular network was 1.6147 ± 0.0151 in segmented variant and 1.5554 ± 0.0239 in skeletonised variant. Also, the mean lacunarity parameterwas 0.5210 ± 0.0343 in segmented version and 0.2916 ± 0.0218 in skeletonised version.