Does the FSH/LH Ratio in the Serum on the Third Day of the Cycle Predict ICSI Success?

Objective: To determine whether the follicule stimulating hormone (FSH)/ luteinizing hormone (LH) ratios on the third day of the cycle predict intracytoplasmic sperm injection (ICSI) outcomes in women with normal day 3 FSH levels.Patients and Methods: A retrospective cohort analysis of one hundred and ninety-nine consecutive women undergoing ICSI treatment with long-down regulation and recombinant follicular stimulating hormone injections was carried out in a University hospital. Four groups were compared in terms of in vitro fertilization (IVF) outcomes. Groups A, B, C and D consisted of women with FSH/LH ratios of <1; ≥1 and <1.5; ≥1.5 and ≤2 and >2, respectively. The clinical pregnancy and implantation rates per transfer were compared.Results: There was no significant difference between the groups regarding the clinical pregnancy or implantation rates per transfer.Conclusion: It appears that the basal FSH/LH ratio does not predict the cycle outcome in ICSI cycles in women with normal day 3 FSH levels. (Marmara Medical Journal 2012;25:69-73)