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Materials 2013
Chitosonic? Acid as a Novel Cosmetic Ingredient: Evaluation of its Antimicrobial, Antioxidant and Hydration ActivitiesDOI: 10.3390/ma6041391 Keywords: antimicrobial activity, antioxidant activity, Carboxymethyl Caprooyl Chitosan, Chitosonic? Acid, cosmetic ingredient, hydration activity Abstract: Chitosonic ? Acid, carboxymethyl hexanoyl chitosan, is a novel chitosan material that has recently been accepted by the Personal Care Products Council as a new cosmetic ingredient with the INCI (International Nomenclature of Cosmetic Ingredients) name Carboxymethyl Caprooyl Chitosan. In this study, we analyze several important cosmetic characteristics of Chitosonic ? Acid. Our results demonstrate that Chitosonic ? Acid is a water-soluble chitosan derivative with a high HLB value. Chitosonic ? Acid can form a nano-network structure when its concentration is higher than 0.5% and can self-assemble into a nanosphere structure when its concentration is lower than 0.2%. Chitosonic ? Acid has potent antimicrobial activities against gram-positive bacteria, gram-negative bacteria and fungus. Chitosonic ? Acid also has moderate DPPH radical scavenging activity. Additionally, Chitosonic ? Acid exhibits good hydration activity for absorbing and retaining water molecules with its hydrophilic groups. From a safety point of view, Chitosonic ? Acid has no cytotoxicity to L-929 cells if its concentration is less than 0.5%. Moreover, Chitosonic ? Acid has good compatibilities with various normal cosmetic ingredients. Therefore, we propose that Chitosonic ? Acid has the potential to be a widely used ingredient in various types of cosmetic products.
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