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OALib Journal期刊
ISSN: 2333-9721
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SYNTHESIS, CHARACTERIZATION, BIOLOGICAL EVALUATION AND ANTI-CORROSION ACTIVITY OF SOME NEW SHIFF BASES DERIVATIVES CONTAINING PIPERIDONE-4

Keywords: Piperidone-4 , Schiff Bases , Antibacterial Activities , Anti-Corrosion Activities , Polarisation , X-Ray Diffraction

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Abstract:

A new Shiff base were synthesis by the reaction of 2,6-bis (4-chlorophenyl) pipridone-4 with benzidine in ratio (2:1) and reaction of 3,5- dimethyl-2,6- diphenyl piperidone-4 with 1,2-Phenylendiamine and 2-aminobenzenethiol in ratio (1:1). All synthesized compound were characterized by melting point, elemental analysis, Ms, FT-IR, one–dimensional NMR (1H&13C) spectroscopic data and evaluated for their in vitro antibacterial activities, against Gram positive (Staphylococcys aureus) and Grame negative (Escherichia.coli, Enterobacter, Salmonella, Klebsiella) bacteria. The synthesized compounds were tested to determine their ability to inhibit corrosion of mild steel in 1 mol.L -1 H2SO4 and measured by polarization measurements and X-ray diffraction.

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