Control of brucellosis in cattle from Durres and Lushnja complexes through the application of Brucella abortus rb51 vaccine control of brucellosis in cattle

Brucellosis is one of the most important zoonotic diseases, epidemiological and bacteriological data of Food Safety and Veterinary Institute in Tirana, confirms the presence of this infection in all farm animals and is extended in the whole country. Monitoring of the epidemiological situation through serological tests carried out in cattle complexes in Durres and Lushnja, confirmed that the prevalence of brucellosis in these complexes were respectively 38.4 and 21.8%. Given of a considerable number of abortions, number of pathological specimens for the isolation of the cause of abortions, were from aborted fetuses, parenchymatous organs of the lymph glands of aborted cows and sera-positive results with serological tests. Based on morphological, biochemical characteristics and agglutination test with typo specific sera causes of abortions were identified as Brucella abortus biotypes 6 and Brucella melitensis biotypes 3, results confirmed by the reference laboratory VLA-London. In this context, the application of the control / eradication strategy of this infection in cattle from Durres and Lushnja complexes through the use of vaccine with strain Brucella abortus RB51 and evaluation of vaccine immunogenicity through brucelina PPD allergen manufactured by us is the main objective of this study. Through the use of this vaccine defined by this study, we obtained the control of Brucella infection in both complexes included in the study and 24 months after the application of the vaccines, complexes are considered to be "free" from brucellosis.