TNF-a TAY N N REFLEKTOMETR K NTERFERANS SPEKTROSKOP S TEMELL SENS R GEL T R LMES

In this work, sensor system based on reflectometric interference spectroscopy has been prepared for selective recognition and binding of TNF-alfa biomolecules. For this purpose, carboxymethyldextran coated and reflectometric interference spectroscopy based sensor systems have been activated for binding of suitable orientated antibody. Then, anti-TNF-alfa antibody has been bound on the surface and binding efficiency and binding constants of prepared sensors have been investigated.