THE EFFECTS OF SOME PESTICIDES ON THE CARDIAC ACTIVITY IN FROG (Rana ridibunda Pall.)

The paper analyses the experimental results on the effects of various doses of Oleokalus insecticide (0.15, 0.75and 1.5 mg%), Oltisan herbicid (0.25, 1 and 2 mg%) and Tilt fungicide (0.25, 1 and 3 mg%) upon the isolated heart offrog (Rana ridibunda Pall.) perfused with a Ringer physiological solution. The doses, similar to those applied inagricultural practice, are considered as non-toxic for the environment (Baicu, 1979). The mechano-cardiogramsperformed showed that all pesticides under analysis cause depression in the cardiac activity of frog, its intensity andpersistence depending on the substance and dose applied. The maximum remanent cardio-inhibiting effects are inducedby fungicide Tilt.