Pharmacological evaluation of Jatropha curcas L. extract for Anti-diarrhoeal Activity

The present study provides the pharmacological evaluation of stem bark extract ofJatropha curcas L. for anti-diarrhoeal activity in rats. We made an attempt to study theeffect of stem bark extract of Jatropha curcas L. on diarrhoeal disease. The differentactivities studied were castor oil-induced diarrhoea, magnesium sulphate induceddiarrhoea and charcoal meal transit test. The result of the study reflected that methanolextract of the stem bark (100, 300 mg/kg) decreased total no. of faeces, wet faeces anddistance travelled by charcoal plug and showed the anti-diarrhoeal activity. Jatrophacurcas L. extract demonstrates the anti-diarrhoeal activity in rats.