GC-HS Method Development for the Estimation of Benzene Content in Lovastatin

A simple, fast and accurate method has been developed for the estimation of benzene content inLovastatin by Gas Chromatography. The analysis was carried out on Perkin Elmer Clarus 600 GC-HSChromatograph. The column used was DB-624 30m X 0.32 mm X 1.8 μm fused silica analytical column(6% cyanopropylphenyl 94 % dimethylpolysiloxane as a stationary phase).The detector used wasFID detector.