EVALUATION OF ANTI HIV-1 ACTIVITY FROM CESTRUM NOCTURNUM AERIAL PARTS AND PHYTOCHEMICALANALYSIS

This study deals with evaluation of HIV-1 activity from Cestrum nocturnum aerial parts extracts and investigation of phytoconstituents in the plant extracts. Different extracts from Cestrum nocturnum aerial parts, methanol 80%, ethyl acetate, butanol and aqueous extracts were tested for their anti-HIV-1 activity using the syncytia formation assay. All the extracts were weak active as anti-HIV-1 agents. Cestrum nocturnum aerial parts extracts contained saponins, triterpenes and/or sterols flavonoids, tannins and coumarins. The extracts from Cestrum nocturnum aerial parts showed a mild anti-HIV-1 activity.