ISOLATION AND DISTRIBUTION OF CANDIDA SPECIES AMONG DIFFERENT CLINICAL SITUATIONS IN CRITICALLY ILL PATIENTS: PROSPECTIVE STUDY

Bloodstream infections due to Candida species are important complications in severely ill hospitalized patients.A change in species distribution has been observed now a day with the emergence of many non-albicans Candida species. The aim of our study is to evaluate the incidence of distribution of different candida species in different clinical condition. Between 2009 and 2011 we encountered 106 episodes of candida species among 412 patients in ICU. Distribution of Candida species among culture positive in different clinical situation like 178 patient receiving TPN, 58 had candida species,124 patient of diabetes 20 had Candia species ,4 HIV patient 3 had Candida glabrata and 1 had C.tropicalis and in neutropenic patient 36 had Candia species out of 82 patient and all had statistically significant, p< 0.05.Among Candida isolates C.tropicalis was predominant species isolated in patient of diabetes, receiving TPN ,cancer and neutropenia.106 of blood Candida isolates were 52 (49.0%) Candida tropicalis, 28 (26.6%) C. albicans, 14(13.5%) Candida gullerimondi, 8 (7.8%) Candida glabrata and 4 (3.8%) were Candida krusei. Organisms were grown in Sabouraud dextrose broth.