A RARE CASE OF PERFORATED GIST OF TRANSVERSE MESOCOLON WITH SYNCHRONUS RECTAL CARCINOMA

ABSTRACT: GISTs are rare neoplasms and represent the 0.1–3% of all gastrointestinal cancers .Although their pathogenesis is known little is known about their coincidence with other tumors of different histogenesis. Surgery remains the mainstay therapy for both (GIST and colorectal cancer) although the operative strategies and extent of resection are fairly different. 1 We report here a case of 68 year old male who presented with a large pedunculated GIST 26cm X 20cmx15cm arising from transverse mesocolon with a small perforation measuring 2x1 cm .Per rectal examination revealed a fungating mass measuring 4x 3cm about 5 cm from anal verge. Histopathologic findings confirmed the presence of colonic GIST with a highly malignant behaviour while rectal biopsy confirmed adenocarcinoma.