Antimicrobial interaction of Lactococcus lactis subsp. lactis against some pathogenic bacteria

A research was conducted to determine the interaction of antimicrobial compound produced by Lactococcus lactis subsp. lactis at various parameters against Salmonella and Staphylococcus aureus. The results showed static effect of antimicrobial compound against the bacteria. Salmonella exhibited the highest inhibition zone of 20.00±1.23mm at selected Lactococcus lactis subsp. lactis at initial substrate pH and temperature, but at different time of culturing period. Staphylococcus aureus showed the highest inhibition zone of 20.00±2.13mm at initial substrate pH 7.0, with Lactococcus lactis subsp. lactis incubation temperature of 37 C at 168 hours. From the above findings, the optimum condition of antimicrobial compound production was 37 C of incubation temperature with pH 7 of initial substrate.