A pilot study of allostatic load among elderly Japanese living on Hizen-Oshima Island

Reported here are preliminary results from this sample of 27 individuals with an average age of 71？years. Their ages ranged from 51 to 82？years, with a standard deviation (sd) of 7.4？years. In total, 33 aspects of physical and physiological variation were assessed on these 15 women and 12 men. As expected from previous studies of Japanese elders, our sample shows slightly elevated average blood pressure (142/81？mmHg, sd 16/10), but they are relatively lean (waist/hip？=？.9: sd 0.06) when compared to European or American standards. However, their average total cholesterol (TC？=？210？mg/dl, sd？=？42.8) is high compared to standards, as is their high-density lipoprotein cholesterol (HDLc？=？55.4？mg/dl, sd？=？15.1). Means, standard deviations (sd), ranges and upper bounds for quartile cut-points for all 10 variables used in the calculation of allostatic load (AL) were assessed. The overall average estimate for AL in this sample is 3.1 (sd？=？1.58) and ranges from 1 to 7.AL shows variability across men and women, has little correlation with age, and is associated with physiological variation in blood glucose, dopamine and uric acid.