THE EFFECTS OF GOLD AND SILVER NANOPARTICLES ON TRANSAMINASE ENZYMES ACTIVITIES

Gold and silver nanoparticles colloids were produced by irradiating a metallic target plates with a thickness of 1mm immersed in distilled water with a pulsed laser beam. The size and size distributions of the metals nanoparticles were examined by the transmission electron microscope TEM analysis. The nanoparticles concentrations were also characterized by atomic absorption spectroscopy AAS measurement. The effects of gold and silver nanoparticles were studied on the activities of GOT and GPT enzymes in the sera. Gold and silver nanoparticles demonstrated inhibitor effects on the (GOT) and (GPT) activities, and these effects increased with increasing the concentrations of the nanoparticles