SOME BIOCHEMICAL PARAMETERS IN IRAQI PATIENTS WITH THALASSEMIA AND RELATED WITH DM1

This paper describe the study of the role of iron and some biochemical parameters in 30 patients with β-thalassemia major with diabetes type 1 (TD), 30 patients with β-thalassemia major as pathological control group(TM),all patients were having chelating therapy (desferrioxamine), and 30 healthy individuals as control group. The age of all studied groups were range from (12-35)years .And attempted to shed a light on thepossible correlation between (Hb,HbA1C,Fe and Insulin)and some parameters (IgM .IgG, IgA, trace elements and ferritin)for TM and TD patients. The results revealed a significant increased in HbA1C ,immunoglobulins , Fe and ferrittin in TM &TD as compared to control ,while a significant decreased in Hb, albumin, total protein ,Cr ,V,TIBC and UIBC in TM &TD as compared to control. The results revealed significant increased insulin in TD, while a significant decreased in TM because of exogenous insulin of TD.