In vitro Antioxidant activity of Methanolic Extract of Syzygium cumini Linn. Bark

The present research was subjected to screen invitro antioxidant activity ofmethanolic extract of Syzygium cumini bark. Preliminary Phytochemicalinvestigation was carried out on the methanolic extract of Syzygium cuminibark. It indices presence of Carbohydrates, Amino acids, Tannins, Saponins,Phytosterols, Terpenoids, phenols and flavones. The antioxidant activity wasdetermined by invitro methods such as 2,2-diphenyl-1-picrylhydrazyl (DPPH)scavenging assay, Hydrogen peroxide scavenging assay, and Ferric reducingantioxidant power (FRAP) assay. The IC50 value of methanolic extract of Syzygium cumini for DPPH and hydrogen peroxide scavenging activity were found to be 53.3% at concentration of 600mg and 42.03% at 1.2mg/ml respectively. FRAP value found to be 810μg Fe2+/gm. The extract showed significant antioxidant activity in all antioxidant assays when compared to ascorbic acid. The results of this research work are promising thus indicating the utilisation of the bark of Syzygium cumini as a significant source of natural antioxidants