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Immune system, immune self. IntroductionKeywords: Immune self , Philosophy of immunology , Self/non-self discrimination , Immunology: Immunity Abstract: The idea that the immune system distinguishes between self and non-self was one of the central assumptions of immunology in the second half of 20 th century. This idea influenced experimental design and data interpretation. However, in the face of new evidence there is a need for a new conceptual framework in immunology.
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