Biological Activities of Some Transition Metal Complexes Derived from Floral Fragrances

Transition metal complexes containing a tridentate N, S, and O donorligand i.e. 3,7-dimethyl-7-hydroxyoctane thiosemicarbazone(DHOTSC) have been synthesized and characterized by elementalanalysis, molar conductance, magnetic susceptibility measurementsand various spectral studies. The ligand DHOTSC acts as ML type complexes M = Cu(II), Ni(II), Cu(II), Zn(II), Cd(II) and Hg(II), L = DHOTSC. The ligand DHOTSC acts as tridentate ligand in allcomplexes. The N, S and O atoms of ligand are involved in coordinationto metal ion. All the newly synthesized metal complexes aswell as the ligand were screened for their antifungal and antibacterial activity. The activities of the complexes are stronger than those of ligand DHOTSC itself.