SCIENTIFIC BASIS FOR THE PREPARATION AND CHARACTERIZATION OF IRON BASED TRADITIONAL DRUG ANNABHEDI SINDOORAM: A MATERIALISTIC APPROACH

Iron based traditional Ayurvedic drug Annabhedi Sindooram is used therapeutically for the treatment of diseases like Anaemia, Leucoderma, Prolapse of rectum and uterus, Spleenic disorders. The preparation method of iron based Indian traditional drug Annabhedi Sindooram involves conversion of a pure metal into its mixed oxide by drying and incineration. Commercially available ferrous sulphate is used as the source of iron for the preparation of Annabhedi. The structural and textural properties of the starting materials and the prepared drug were characterized systematically by different characterization techniques like PXRD, Zeta Potential Analysis, particle analysis, FTIR, ICP –AES, SEM and BET surface area analysis. The results obtained by characterization of the samples clearly explain the formation of Fe2O3, reduction in particle size, modification of surface energy and formation of metal complex with organic moieties. The strict post and pre preparation conditions followed play an important role in the morphology and medicinal activity of the drug Annabhedi Sindooram.