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Journal of Biology 2009
The genomic 'inner fish' and a regulatory enigma in the vertebratesDOI: 10.1186/jbiol131 Abstract: Information on how genomic information from fish to human encodes the same tissues has until now emerged one gene at a time. The study published in this issue now provides lists of genes and their expression levels for 20 vertebrate tissues spanning 450 million years of vertebrate evolution. It reveals a core set of genes with similar tissue-expression patterns yet no common regulatory signatures – a gene-expression paradox.
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