Letter to the editor

Vito D’Alessandro,1 Mario Greco21Respiratory Oncology Section – Internal Medicine Department, 2Hematopoietic Stem Cell Transplantation Unit Hematology-Oncology Department, of Scientific Institute, “Casa Sollievo della Sofferenza” Hospital, San Giovanni Rotondo (FG), ItalyWe particularly appreciated the recent successful attempt at review of management of tumor lysis syndrome, entitled “Emerging role of rasburicase in the management of increased plasma uric acid levels in patients with hematologic malignancies”1 which reported some practical management considerations and financial implications of a complex subject. The praiseworthy aim was to give clear and easily applicable indications for clinical practice from recently published off-label treatment studies, using lower and fewer doses of rasburicase than recommended.View original paper by Kennedy and colleagues.