7-Nitroindazole and its rapidly emerging role in opioid pain management and withdrawal

Shailendra KapoorRichmond, VA, USAI read with great interest the paper by Jin et al in a recent issue of your journal.1 The article is highly thought-provoking. Interestingly, the past few years have also seen the emergence of nitric oxide synthetase inhibitors, especially 7-nitroindazole, as novel new agents with significant benefits in opioid pain management and withdrawal. View original paper by Jin and Loscalzo.