Severe Aripiprazole-Induced Extrapyramidal Parkinsonian Features In A Patient With Psychotic Depression On Sertraline: A Case Report

Aripiprazole is a third generation antipsychotic with partial dopaminergic activity. In addition to its proven antipsychotic effects, it has become more widely accepted at the clinical level. It is FDA-approved as an adjunctive therapy for depression with or without psychotic features. This case report concerns the development of severe Parkinsonian features in a depressed psychotic patient following the addition of aripiprazole to his sertraline treatment.