A survey of hypertension and hyperandrogenemia in the first degree relatives of women with polycystic ovarian syndrome referring to gynecology clinics of Shiraz Medical University

Introduction:Polycystic ovarian (pco) syndrome is one of the most prevalent (4-8%) endocrine glands disorders among women15-45 years old. In women with polycystic ovary syndrome (pcos), increased blood pressure and abnormal androgen are prevalent. In addition to the patients, their first degree relatives are exposed to some risk factors such as hypertension and hyperandrogenemia. Due to the high prevalence of pcos among women and its outcomes among their first degree relatives, it is necessary to recognize the high risk people. This study was conducted to survey hypertension and hyperandrogenemia in the first degree relatives of patients with polycystic ovarian syndromeMaterial and Methods:This is a case-control study in which 107 individuals as case group and 107 individuals as control group were selected from among the first degree relatives of women with polycystic ovarian syndrome in 2008. The participants filled in a questionnaire on demographics. Then their blood pressure was measured and blood samples were taken from all the participants in order to assay their serum androgens. After performing biochemical tests, data were gathered and analyzed by Chi square and Kapa tests with 95% confidence intervals and alpha coefficients 0.05. Results:The mean of the total androgens and high level blood pressure of the control group were much different from those of the case group (P<0.05).Conclusion:The first degree relatives of women suffering from polycystic ovarian syndrome are probably exposed to abnormal blood pressure and hyperandrogenemia.