Causative agents and antibiotic susceptibilities in children with urinary tract infection

Objectives: Nowadays, it has become more difficult treatment of the urinary tract infections because of developing high antibiotic resistance. The aim of this study was to investigate the most common causative microorganisms, their susceptibility and resistance to antibiotics in childhood urinary tract infections (UTI).Materials and methods: In this study, data belonging to urinary culture of 111 children with the diagnosis of UTI at Dicle University Medical School, Department of Pediatrics, throughout 1.5 years.Results: Of all cases 97 (87.4%) were female and 14(12.6%) were male. The most common complaints of children were dysuria, fever, flank pain and pollakiuria. Isolated microorganisms according to decreasing frequency were E.coli (75.7%), Klebsiella sp (7.2%), Proteus sp (6.3%) and Enterobacter sp (1.8%). The resistance rates against trimethoprim-sulfamethoxazolewas 71.3%, ampicillin 82.4%, amoxicillin-clavulanate 54.7% and tetracycline 68.3%, and the least resistance rates were for ceftriaxone (16%) and amikacin (8.1%).Conclusion: In conclusion, the most common causative agent was E.coli and the highest resistance ratios were against trimethoprim-sulfamethoxazole, ampicillin and amoxicillin-clavulanate in children with UTI that presented in this study. Fewest ratio of resistance was found against amicasin and cephtriaxone. J Microbiol Infect Dis 2011;1(1):17-21.