Multifocal peripheral odontogenic fibroma

A 35-year-old woman was presented with diffuse, sessile, firm, and exophytic lesions in molar premolar region in both the jaws. The patient had poor oral hygiene, with grade I mobility of first molars in both the jaws. Orthopantamograph showed horizontal bone loss in relation to the same. A clinical diagnosis of hyperplastic gingivitis was made. Incisional biopsies followed by microscopic examination revealed a pattern of peripheral odontogenic fibroma (WHO type). Peripheral odontogenic fibroma (POdF) is characteristically described as a solitary neoplasm, and very few cases of diffuse peripheral odontogenic fibroma have been reported in literature. Despite the rarity of POdF presenting as a diffuse lesion, the lesion should be included as a possible differential diagnosis of diffuse single or multiple gingival lesions.