Comparative Antimicrobial Studies of Dioscorea Hamiltonii hook.f.tubers with Azadirachta Indica Stem

Antimicrobial activity of tuber extract of Dioscorea hamiltonii Hook.f. and stem extracts of Azadirachta indica was comparatively studied against Aspergillus niger, Bacillus subtilis, Enterococcus faecalis, Escherichia coli, Lactobacillus delbrueckii subsp lactis, Penicillium chrysogenum, Proteus Vulgaris, Pseudomonas aeruginosa,Saccharomyces cerevisiae, Streptococcus pyogenes, Streptococcus thermophilus and Vibrio parahaemolyticus. Methanolic and Ethyl acetate leaf extracts from D.hamiltonii and A.indica has shown good antimicrobial activity against tested microbes (9 to 25mm zone diameter). The extract has shown good activity against Gram positivebacteria (14 to 25mm), when compared with Gram negative bacteria (12 to 23) and fungi (9 to 15mm, except S.cerevisiae-17 to 24mm). Higher concentrations of extracts are required to retard the growth of fungi.