Anti microbial activity of Methanol Extract of Oxystelma Esculentum

Bacterial and fungal infections were some of the most serious global health issues of the present century. Numerous biologically active plants have been discovered by evaluation of ethnopharmacological data and these plants may offer the local population immediately accessible therapeutic products. Several herbs were known to possess medicinal value including anti-microbial properties. Oxystelma esculentum is used medicinally in Egypt. Different parts of these plants have been claimed to be effective in a wide spectrum of diseases. Thestudy was based on the effect of herbal medicine or natural products on candidiasis which is a fungal disease caused by the fungi Candida albicans. The present investigations were, therefore, proposed in evaluate the efficacy of the methanol extract of Oxystelma esculentum (MEOE). The antibacterial studies confirmed that MEOE had zone of inhibition, but the MIC of MEOE is 500 g/ml in two fold serial dilution method ensuring no prominent action on the tested bacterial strains.The antifungal studies confirmed that MEOE had a effectivezone of inhibition against C. albicans and C. neoformans. In MIC studies, the MEOE had more effect on C. albicans, thus giving a lead for further in vivo anticandidal studies.