ANTIOXIDANT EFFECTS OF MUEHLENBECKIA HASTULATA J. (POLYGONACEAE) EXTRACTS

The antioxidant properties of different extracts of quilo (Muehlenbeckia hastulata J., Poligonaceae) herb from Valparaíso region in Chile were evaluated. Antioxidant activity was assessed in three different model systems. Antioxidant models were examined by measuring the scavenging activity of extracts on 2,2-diphenyl-1-pycrylhydrazil (DPPH*). Moreover extracts were evaluated by ferric reducing antioxidant power (FRAP) and the total peroxyl radical-trapping potential (TRAP). The amount of dried extract, the content of total phenolics, flavonoids, hydrolyzed sugar and anthraquinones were also determined. Extracts pertaining to stem and root of the plants were the significant activities DPPH radical scavenging (IC50 0.74 mg/mL to 1.33 mg/mL the more active extracts). The activities and TRAP and FRAP high values in extracts of EtOAc (1.423 and 1.540 mM TEAC) and ethanol (245.26 and 309.04 mM TEAC) stem and root of the plant are higher.The observed differences in antioxidant activity among the different parts of quilo could be partially explained by the levels of phenolics compounds present in the root extract of EtOAc (0.023 mg GAE/g dry extract), flavonoids in the leaves of EtOAc extract (99.12 mg QE/g dry extract), hydrolyzed sugar in the ethanol extract (21.87, 14.85 and 14.32 mg GES/ g dry extract of leaf, stem and roots, respectively) and anthraquinones in the EtOAc extracts (2.50, 1.43 and 0.84 mg EE/ g dry extract of leaf, stem and roots, respectively) .