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Phytochemical Screening and Antibacterial Activity of Combretum glutinosum Extract against Some Human Pathogens

Keywords: Combretum glutinosum , enteric infections , methanolic extract , phytochemicals

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Abstract:

The aim of this study is to determine the antibacterial effects of Combretum glutinosum plant extract on some clinically isolated bacteria species. Combretum glutinosum powdered plant materials was extracted using methanol and sterile distilled water. The Agar diffused methods was used to determine the antimicrobial activity of the plant against Salmonella typhi, Pseudomonas aeruginosa, Staphylococcus aureus and Escherichia coli. The methanolic and water both provide yield from different parts of the plant and both showed effectiveness. Phytochemical screening of the crude extract revealed the presence of tannins, saponins, phenolcs, flavonoids, cardiac glycosides, anthroquinones and alkaloids and the growth of all bacteria were inhibited though to varying degrees thus justifying their use in traditional medicines in treating enteric infection and other diseases across Africa.

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