EFFECT OF 12 WEEKS HIGH INTENSITY AEROBIC EXERCISE ON SERUM OXIDIZED LDL-C IN OBESE MIDDLE AGED MEN

MOGHADASI, M.; HEIDARNIA, E.; NEMATOLLAHZADEH, M.; TORKFAR, A.; ARVIN, H. Effect of 12 weeks high intensity aerobic exercise on serum oxidized LDL-c in obese middle aged men. Brazilian Journal of Biomotricity. v. 5, n. 4, p. 263-270, 2011. Exercise significantly influences the progression of atherosclerosis. Oxidized LDL-c (ox-LDL-c), as a stimulator of oxidative stress, facilitates monocyte-related atherogenesis. We investigated the effect of 12 weeks high intensity aerobic exercise on serum oxidized LDL-c in obese middle aged men. Sixteen sedentary obese middle-aged men (aged: 41.18±6.1 years; ±SD) volunteered to participate in this study. The subjects were randomly assigned to training group (n=8) or control group (n=8). The training group performed endurance training 4 days a week for 12 weeks at an intensity corresponding to 75-80% individual maximum oxygen consumption for 45 min. High intensity aerobic exercise did not significantly alter serum ox-LDL-c, total cholesterol (TC) and low-density lipoprotein (LDL-c), while serum high-density lipoprotein (HDL-c) and triglyceride (TG) were significantly increased and decreased respectively (P<0.05). There were significant positive correlations between LDL-c and TC with ox-LDL-c (P<0.05) and a significant negative correlation between HDL-c and TG (P<0.05). We conclude that serum ox-LDL was not affected by high intensity aerobic exercise.