A Case Report of the Effect of Noni Juice on Crohn’s Disease

The aim of the current case study was to evaluate the possible role of noni juice in the improvement of Crohn’s disease symptoms. A 35-year-old male suffered from Crohn’s disease for more than 10 years. Treatment prior to consumption of noni juice involved multiple monthly adalimumab injections, which lowered C-Reactive Protein (CRP) levels to 1.2 mg/L, even though symptoms persisted. Six months after he began drinking noni juice, including one month of consuming a combination of noni juice and olive leaf extract, his symptoms improved and CRP decreased to 0.0 mg/L. These improvements accompanied gradual decreases in adalimumab injection frequency, followed by cessation altogether. Noni juice possesses anti-inflammatory properties that involve multiple mechanisms, including immunomodulation. Relevant experimental data are reviewed and discussed within the context of this case.